YK11 Powder

YK11 Powder Sarm Finland

YK11 is a synthetic steroidal selective androgen receptor modulator (SARM) that attracts attention for its potential impact on skeletal muscle growth and performance. Finland Research shows YK-11 acts as a partial agonist of the androgen receptor (AR). It targets genes like myostatin (GDF8), drives myogenic differentiation, and regulates mRNA expression. This compound may promote rapid muscle gains because it works as a novel selective androgen receptor modulator (more precisely, it has a steroidal structure similar to DHT), a strong hormone linked to androgenic effects.

Moreover, YK-11 works by indirectly inhibiting myostatin through higher Follistatin expression. By modulating these pathways, YK-11 may support muscle development and strength gains, making it appealing to individuals seeking better physical performance.

Additionally, recent studies explored YK-11’s impact on oxidative stress and mitochondrial function in the hippocampus. These findings hint at broader implications beyond muscle benefits. The link between YK11, oxidative stress, and mitochondrial dysfunction in the memory and learning region of the brain creates new opportunities for studying its effects on cognitive function.

Benefits of YK11 Powder SARM Finland

Increased Muscle Mass and Strength

YK11, often called a SARM but actually a potent myostatin inhibitor, may improve building muscle in a unique way. It blocks myostatin, the protein that limits muscle fiber growth and differentiation, which may allow development beyond hereditary limits. YK-11 also triggers androgen receptor activation, boosts anabolic pathways in cells, increases protein production, and supports lean body mass.

Finland Lab research reported quick muscle gains, higher strength, and less muscle loss. But any drug administration of experimental agents like YK-11 needs careful study. A systematic review must fully evaluate its potential risks, especially compared with anabolic androgenic steroids.

Improved Bone Health

Protein kinase B (PKB) activation in cells sends signals that promote bone growth, and YK11 appears to raise these levels. Like other commonly studied anabolic steroids, YK-11 is under investigation for osteogenic activity. In Finland mouse studies, YK11 increased bone density and bone strength. These findings suggest YK-11 may help treat osteoporosis and other bone-weakening conditions.

Reduced Fatigue

According to anecdotal reports, YK-11 may reduce fatigue and improve endurance. By supporting recovery and reducing muscle exhaustion, it may increase stamina during exercise. Some users report feeling more energized and able to sustain intensive workouts after using YK11, suggesting it may help fight fatigue and improve endurance. Some also claim it causes fewer side effects compared with androgenic steroids, especially when combined with proper cycle support. Still, higher doses may increase its side effect profile, and more research must confirm these effects.

Cognitive Function

Early studies proposed that androgens directly affect thinking and memory. Because YK-11 has a steroidal structure, researchers believed it works on androgen receptors, similar to testosterone. This led them to expect possible cognitive benefits.

Later animal studies showed different results. Scientists found YK11 caused oxidative stress and disrupted mitochondria in the hippocampus, the brain’s memory center. These problems reduced memory formation, suggesting YK-11 may harm cognitive health. So far, studies in humans have not confirmed these risks.

Additional Considerations

Finland Researchers compare YK-11 to growth hormone enhancers and cycle therapy routines because of its recovery effects. But unlike a true SARM, YK11 may suppress natural testosterone production. Reports show testosterone suppression, which may require adjustments to cycle length or the use of post-cycle therapy. Researchers strongly advise monitoring liver enzymes and testosterone production when using YK-11 for research purposes. Some athletes add the use of testosterone alongside YK-11 to offset suppression, but this practice carries its own risks.

Researchers often list YK-11 among the most potent SARMs because of its high binding affinity, potential role in fat loss, possible joint support, and its effect on muscle development. However, due to its similarities with anabolic androgenic steroids and androgenic steroids, experts continue to warn that significant risks remain.

Is YK-11 Legal?

YK11 is currently classified as a research chemical, and regulators such as the FDA and EMA do not approve it for human use. Companies can usually sell it only for laboratory and research purposes. While YK-11 is not a controlled substance in many countries, local laws may differ.

The World Anti-Doping Agency (WADA) bans YK-11 in sports because it acts like anabolic androgenic steroids and has androgenic effects. Anyone interested in YK-11 should check their local laws since rules change by country.

All information about YK-11 is based on preclinical research, including animal and cell studies. Human clinical data is limited, and YK-11 is not approved for human consumption. It is sold strictly for laboratory and research purposes only.

Like our YK11 SARM Powder? Shop more YK-11 SARM products here from Direct SARMS Finland

References:

[1] Yatsu T, Kusakabe T, Kato K, Inouye Y,et al. Selective Androgen Receptor Modulator, YK 11, Up-Regulates Osteoblastic Proliferation and Differentiation in MC3T3-E1 Cells. Biol Pharm Bull. 2018;41(3):394-398.

[2] Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM. Myostatin inhibitor YK 11 as a preventative health supplement for bacterial sepsis. Biochem Biophys Res Commun. 2021 Mar 5;543:1-7. d

[3] Dahleh MMM, Bortolotto VC, Boeira SP, Segat HJ, et al. From gains to gaps? How Selective Androgen Receptor Modulator (SARM) YK 11 impact hippocampal function: In silico, in vivo, and ex vivo perspectives. Chem Biol Interact. 2024 May 1;394:110971.

[4] Dahleh MMM, Bortolotto VC, Guerra GP, Boeira SP, Prigol M. YK 11 induces oxidative stress and mitochondrial dysfunction in hippocampus: The interplay between a selective androgen receptor modulator (SARM) and exercise. J Steroid Biochem Mol Biol. 2023 Oct;233:106364.

[5] Kanno Y, Hikosaka R, Zhang SY, Inoue Y, Nakahama T, Kato K, Yamaguchi A, Tominaga N, Kohra S, Arizono K, Inouye Y. (17α,20E)-17,20-[(1-methoxyethylidene)bis(oxy)]-3-oxo-19-norpregna-4,20-diene-21-carboxylic acid methyl ester (YK 11) is a partial agonist of the androgen receptor. Biol Pharm Bull. 2011;34(3):318-23.

Molecular Formula: C₂₀H₂₄ClN₃O₄S
Molecular Mass : 437.94026 g/mol

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DISCLAIMER: These products are intended solely as a research chemical only. This classification allows for their use only for research development and laboratory studies. The information available on our Finland Direct Sarms website is provided for educational purposes only. These products are not for human or animal use or consumption in any manner. Handling of these products should be limited to suitably qualified professionals. They are not to be classified as a drug, food, cosmetic, or medicinal product and must not be mislabelled or used as such.

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